Clin Nutrition: The effects of short -term and long -term results of gastric cancer gastric sorceration after gastric cancer

Gastric section is the main method of treatment of gastric cancer patients. The combination of surgery and chemotherapy and multi -mode treatment has increased the survival rate of removed gastric cancer patients. Although the improvement of preoperative diagnosis, surgery and perprore surgery reduced the mortality after gastric section, postoperative complications and recurrence rates were still relatively high. According to reports, the body composition evaluated by skeletal muscles and internal organs will affect the risk of postoperative complications and the prognosis of gastric cancer surgery, especially in the gastrointestinal gastrointestinal surgeon.

Recent studies have shown that young muscle obesity is a bad prognosis of patients with liver cell carcinoma, patients with pancreatic cancer, and patients with liver transplantation. Although it is reported that young muscle obesity is a risk factors for cancer gastric dehumidification, the relationship between body components (such as minor muscle obesity) and cancer gastric removal is still unclear. This study aims to evaluate how the body composition affects the results of the surgical and patient survival.

Researchers reviewed the clinical data of 518 patients in 518 patients due to cancer gastric section from 2004 to 2017. Measure the skeletal muscle quality (skeletal muscle quality index (SMI)) and visceral obesity (visceral fat area) in the computer fault scanning image to classify the patients and study the effects of these physical components on the results of the postoperative results of gastric section. Essence

The physical composition of 231 patients (45%) was classified as high SMI without obesity, 202 patients (39%) were high SMI with obesity, 55 patients (11%) were low SMI without obesity, 30 patients (6%%) (6%%) (6%%) (6%%) ) For low SMI with obesity. 128 patients (25%) had postoperative complications. Multi -variable analysis determines that low SMI and obesity are independent risk factors for postoperative complications (advantages ratio, 3.27; P = 0.010). In addition, the 5 -year total survival rate of patients with low SMI but not obese is lower than SMI but no obesity (64.4% vs. 88.0%; P <0.001), and the 5 -year -no -incident rate is worse (61.3% vs. 81.3%; P = 0.002). Multi -variable analysis determines that low SMI without obesity is the important risk factors of gastric depression (risk ratio, 3.033; P <0.001) and no repetition period (risk ratio, 2.144; P = 0.008).

This study confirmed that low SMI merging obesity before surgery is an independent risk factor for postoperative complications, and non -obesity low SMI is an independent risk factors for the overall survival and recurrence survival of cancer gastric section.

Primitive source:

TSUNEYUKIUCHIDA. Et Al. Impact of Body Fat and Muscle Quantity on Short-And Long-Term Outcom After Cancer. Clinical Nutrition.2022.

Author: xuyihan

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