JEADV: Complications of dermatitis ignored: depression

Specialty dermatitis (AD) is related to psychological social disorders, such as depression, anxiety and suicide. Treat Germany is a multi-center academic registration agency for long-term observation of patients with medium-severe special dermatitis (AD). This article is intended to identify the factors associated with depressive symptoms from the Treat Germany registry (including the Treat Germany registry from June 2016 to the Treat Germany registry). Current surveys include the diagnosis of medical (such as depression) and clinical symptoms (Easi-score), severity (POEM-Scle), Skin-score (POEM-SCORE) Quality (DLQi-Score), and Depressive Symptoms (Popology Research Center Depression Table (CESD Rating)).

The average age of the study is 41.9 years (standard deviation (SD): ± 14.4 years old, including 375 (40.7%) women. Most patients appear to be medium to severe AD (EASI rating ≥ 6, 77.4%, N = 705), and AD affects daily lives (DLQi score ≥ 6, 73.0%, n = 672).

9.7% (N = 89) patients reported depression in the diagnosis of medical treatment. Patients who registered with depression significantly more age (average, SD: 45.2Y ± 13.3Y vs. 41.5Y ± 14.3Y, P = 0.021), reported quality damage significantly larger (DLQi rating: mean, SD: 14.6 ± 8.3 vs. 11.4 ± 7.7, P <0.001), CESD scores higher (average, SD: 23.9 ± 12.0 vs. 13.4 ± 9.1, P <0.001) compared to patients with no depression.

Further CESD score analysis was determined, 0.2% (n = 2) met the possible severe depression, 36.8% (n = 339) was at a depressed symptoms. 70.5% (N = 62) of registration depression has at least a subclinical related depression symptom. This ratio is 33.1% (n = 273) in patients with no depression as a common case. Both results showed the dependence and high CESD score (P <0.001) with depression.

Comparing the symptoms of CESD scores, registration patients scored the highest in sleep, fatigue and incompativity. More women (45.6%, N = 170) were exhibited at least in subclinical associated depression (P <0.001) compared to male registration patients (31.9%, n = 170).

In contrast to previous reports on the increase in depression in the ordinary population, we found that the risk of clinical depression symptoms in more receruptial registered patients with young adults. Our EASI score results show that the more serious clinical symptoms, the stronger the depression symptoms. This is consistent with the previous results. Compared to patients with anti-depressed diseases, AD patients with depression and common diseases have a significant report on symptoms. In addition, past surveys show that sleep is a related factor in patients with AD, especially related to their quality of life. In contraction with these results, we found that there is an association between the sleep component form and the clinical symptom, the severity of the symptoms (poetry-Score) and the DLQi-Score damage. The current problem highlights the associated role of depressive symptoms in high proportions - severe AD adult patients.

The results show that the clinical symptoms are weak, and the quality damage and the frequency of AD symptoms are closely related to depression. The main clinical related impacts include, especially those who are young women, if they often have related issues and / or sleep problems in their daily lives, should be performed by depression.

Source: Helmert C, Haufe E, Heinrich L, Letter to The Editor: Atopic Dermatitis and Depression Symptoms. Results of The German National Ad Registry TreatgerMany.j EUR ACAD DERMATOL VENEREOL 2021 NOV 15;

Tip: The content of this article is for reference only, please refer to the consultation results of regular hospitals!